To navigate, press the arrow keys. Comfort Inn and Suites is perfectly located for both business and leisure guests in Santee (SC). The hotel offers a wide range of amenities and perks to ensure you have a great time. Wi-Fi in public areas, car park are on the list of things guests can enjoy. Designed for comfort, selected guestrooms offer wake-up service, desk, alarm clock, television, satellite/cable TV to ensure a restful night. The hotel offers various recreational opportunities. Comfort Inn and Suites combines warm hospitality with a lovely ambiance to make your stay in Santee (SC) unforgettable.